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The name Lillie originates from "lily" as her white dress resembles the white petals of a lily flower as well as the name following the plant-based naming of characters. Lillie also decides to go to Kanto to become a true Pokémon Trainer so that she may earn badges and meet and catch lots of wonderful Pokémon. Lillie eventually decides to travel to Kanto to find Bill so that he may give her the cure for Nihilego's poison. After Lusamine gets separated from Nihilego, she regains some of her sanity back and touches Lillie's cheek. When the player character and Lillie meet Lusamine in Ultra Space, she gets the courage to yell at Lusamine for being terrible for trying to control her and stating that "children are not just things that belong to their parents". She became unbearable to Lillie, so she left as well. However, over time, Lusamine started becoming insane and grew even madder when Gladion escaped Aether Foundation two years before the story begins. 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